Can taking Tylenol (acetaminophen) before the COVID-19 vaccine reduce its effectiveness?

Can taking Tylenol (acetaminophen) before the COVID-19 vaccine reduce its effectiveness?

Because taking over-the-counter painkillers before getting vaccinated may reduce the responsiveness of your immune system and therefore weaken the effectiveness of the vaccine, the CDC does not recommend taking Tylenol or ibuprofen before getting the COVID-19 vaccine. Dec 17, 2021